Sens4IVD. Biosensing devices for in vitro diagnostics
Project reference
PID2022-136453OB-I00
Programme and call for tender
Ministerio de Ciencia e Innovación (MICINN)
Principal Investigator
Isabel Pividori /Mercè Martí (CoIP)
Duration
1/09/23 – 31/08/26
The SenS4IVD proposal aims at designing in vitro diagnostic (IVD) tests to reliably identify the nature and characteristics of a disease in the early stage, focusing on quantifying biomarkers of different nature, envisioning primary applications in healthcare. This will be achieved by developing an innovative IVD device, combining magnetic actuation and electrochemical biosensing in a portable reader operated by batteries. The long-term vision of the SenS4IVD approach is based on an agnostic platform for the quantification of all types of biomarkers, regardless of their nature, which can be easily switched to emerging challenges. SenS4IVD will drastically shorten the results time, by quantifying proteins, exosomes, transcripts, DNA, or miRNA biomarkers down to a low concentration range in a simplify analytical procedure for the end-user. Such a IVD test can be used both in low resource settings where high-quality gold-standard laboratory tests are not available, and in high-income countries to dramatically improve turnaround times for results to reduce costs. The outcomes achieved by SenS4IVD will enable decision-making of clinicians toward a personalized medicine, for an accurate diagnosis in some instances, or the monitoring of disease treatment in other applications, thereby improving the quality of life and reducing costs in the healthcare systems. The validation of the proof of concept is envisaged with a broad range of targets identified by key opinion leaders in emerging infection diseases, immunology, and cancer, taking as reference communicable diseases (by monitoring the cellular immune response and the molecular signature in exosomes released due to infection), non-communicable diseases (such as breast cancer), and bacteria affecting water sources. A coherent business-focused analysis of research and innovation bottlenecks and opportunities to further societal challenges related with health and wellbeing will be assessed. This, in combination with a valorization and commercialization plan, will pave the way for future large-scale implementation of the SenS4IVD prototypes.
This three year project is funded by Ministerio de Ciencia e Innovación (MICINN)
SCIENTIFIC CONFERENCES, ORAL COMMUNICATIONS AND WORKSHOPS
Conference Contributions (Invited)
Pividori, M.I. “Bridging biosensing technologies from lab to life” (Keynote lecture), XXIX Transfrontier Meeting on Sensors and Biosensors (TMSB), El Teatret, Serrallo, Tarragona (Spain), 18–19 September 2025.
Pividori, M.I. “Exosomas: fuentes, composición y métodos de caracterización y cuantificación”, Jornada Exosomas: de mensajeros a ingredientes, Sociedad Española de Químicos Cosméticos (SEQC), Barcelona (Spain), 8 July 2025. Keynote lecture
Pividori, M.I. “Health Tech en xarxa: experiències de cocreació i transferència”, XII Fòrum de Tecnologies i Innovació – Health Tech, Centre d’Empreses Industrials de Can Roqueta, Sabadell (Spain), 18 June 2025. Invited speaker, round table
Pividori, M.I. “Projectes en col·laboració publicoprivada: reptes, beneficis i estratègies d’èxit” (Webinar participant), Sessió informativa organitzada pel Parc de Recerca UAB sobre la convocatòria de l’Agència Estatal d’Investigació (AEI) “Proyectos en colaboración público-privada”, evento en línea (Microsoft Teams), 15 January 2025.
Pividori, M.I. “Panel participation on agile codesign and industrialization of medical devices” (Invited panelist), Health Revolution Congress (HRC) – Tech Session: New Era on Medical Devices: Agile Codesign, Prototyping & Industrialization, organized by Eurecat and Barcelona Health Hub, Recinte Modernista de Sant Pau, Barcelona (Spain), 16 May 2024.
Pividori, M.I. “Portable biosensing device for environmental and industrial microbiology” (Keynote lecture), SUSNANO Spring School – Electrochemical Nanobiosensors for Environmental Diagnostics (International Conference), ICN2, Barcelona (Spain), 16 April 2024.
Conference Contributions (Awarded)
del Valle, A., Mesas, M., Pallarès-Rusiñol, A., Martí, M., Baró, B., Ferrer-Dalmau, J., Bassat, Q., Pividori, M.I.“Portable PCR and electrochemical genosensing for a rapid screening test development to detect neonatal Streptococcus agalactiae infections” (Oral, Award to Best Oral Presentation), XXVIII Transfrontier Meeting on Sensors and Biosensors, La Ràpita (Spain), 26–27 September 2024.
Bernuz, M., Porras, J.C., Egri, N., González-Navarro, E.A., Juan, M., Pividori, M.I., Martí, M. “Rapid Diagnostic Test for Assessment of Cellular Immune Response in a Viral Infection as a Model” (Poster), XV Jornada del Departament de Biologia Cel·lular, Fisiologia i Immunologia de la UAB, Universitat Autònoma de Barcelona (Spain), 13 June 2024. Best poster award
Conference Contributions (oral and poster communications)
Mesas, M., Molina-Moya, B., de Araújo, B.C., Pallarès-Rusiñol, A., Ferrer-Dalmau, J., Boldrín Zanoni, M.V., Domínguez, J., Julian, E., Pividori, M.I. “Mycobacterium detection method combining filtration, immunomagnetic separation, and electrochemical readout in a portable biosensing device” (Poster), Euroanalysis 2025, Barcelona (Spain), 31 August – 4 September 2025.
Mesas, M., del Valle, A., Martí, M., Pallarès-Rusiñol, A., Ferrer-Dalmau, J., Baró, B., Bassat, Q., Pividori, M.I.“Rapid Stratification of Fever Syndromes using a Traffic Light-based biosensor for sTREM-1” (Poster), Euroanalysis 2025, Barcelona (Spain), 31 August – 4 September 2025.
Rossi, R., Capdevila, M., Cano, A., Ruíz, A., Marti, M., Pividori, M.I. “In-vitro diagnostic test based on exosomes for early diagnosis of Alzheimer’s disease and risk stratification of patients” (Virtual oral onsite poster), AD/PD 2025International Conference on Alzheimer’s and Parkinson’s Diseases and related neurological disorders, Vienna (Austria), 1–5 April 2025.
Capdevila, M., Puerta, R., Rossi, R., Montrreal, L., (…), Cano, A. “Plasma extracellular vesicles show Alzheimer’s disease proteomic hallmarks in patients of a memory clinic” (Poster), AD/PD 2025 International Conference on Alzheimer’s and Parkinson’s Diseases and related neurological disorders, Vienna (Austria), 1–5 April 2025.
Mesas, M., del Valle, A., Marfà, J., Porras, J.C., Pallarès, A., Ferrer-Dalmau, J., Martí, M., Pividori, M.I. “Portable electrochemical biosensing device for point-of-care diagnostics. Applications in communicable diseases” (Oral), XXVIII Galician-Portuguese International Conference on Chemistry, Vigo (Spain), 13–15 November 2024.
Rossi, R., del Valle, A., Pallarès, A., Martí, M., Pividori, M.I. “Biosensing platforms for exosome detection in liquid biopsies. Applications in cancer diagnostics” (Oral), XXVIII Galician-Portuguese International Conference on Chemistry, Vigo (Spain), 13–15 November 2024.
Mesas, M., del Valle, A., Marfà, J., Porras, J.C., Pallarès-Rusiñol, A., Ferrer-Dalmau, J., Rossi, R., Martí, M., Pividori, M.I. “Portable biosensing device for in vitro diagnostic” (Oral), 13º Congreso Iberoamericano de Sensores (IBERSENSOR 2024), Buenos Aires (Argentina), 21–24 October 2024.
Mesas, M., del Valle, A., Pallarès-Rusiñol, A., Ferrer-Dalmau, J., Martí, M., Baró, B., Bassat, Q., Pividori, M.I.“Traffic light-based point-of-care test for the rapid stratification of fever syndromes” (Oral), 13º Congreso Iberoamericano de Sensores (IBERSENSOR 2024), Buenos Aires (Argentina), 21–24 October 2024.
del Valle, A., Mesas, M., Pallarès-Rusiñol, A., Martí, M., Baró, B., Ferrer-Dalmau, J., Bassat, Q., Pividori, M.I.“Rapid screening test for Streptococcus agalactiae neonatal infections combining portable PCR and electrochemical genosensing” (Poster), 13º Congreso Iberoamericano de Sensores (IBERSENSOR 2024), Buenos Aires (Argentina), 21–24 October 2024.
Rossi, R., Capdevila, M., Cano, A., Ruíz, A., Marti, M., Pividori, M.I. “In-vitro diagnostic test based on exosomes for early diagnosis of Alzheimer’s disease and risk stratification of patients” (Poster), XXVIII Transfrontier Meeting on Sensors and Biosensors, La Ràpita (Spain), 26–27 September 2024.
Marfà, J., Pividori, M.I. “Integration of molecularly imprinted polymers into paper-based nucleic acid lateral flow platforms for enhanced multiplexed point-of-need diagnostics” (Poster), XXVIII Transfrontier Meeting on Sensors and Biosensors, La Ràpita (Spain), 26–27 September 2024.
Porras, J.C., Pallarès-Rusiñol, A., Alemany-López, K., Ferrer-Dalmau, J., Pividori, M.I. “Portable Medical Device Based on Magneto Immunosensor for the Diagnosis of Celiac Disorder” (Oral), XXVIII Transfrontier Meeting on Sensors and Biosensors, La Ràpita (Spain), 26–27 September 2024.
del Valle, A., Mesas, M., Pallarès-Rusiñol, A., Martí, M., Baró, B., Ferrer-Dalmau, J., Bassat, Q., Pividori, M.I.“Portable PCR and electrochemical genosensing for a rapid screening test development to detect neonatal Streptococcus agalactiae infections” (Oral, Award to Best Oral Presentation), XXVIII Transfrontier Meeting on Sensors and Biosensors, La Ràpita (Spain), 26–27 September 2024.
Mesas, M., del Valle, A., Martí, M., Pallarès-Rusiñol, A., Ferrer-Dalmau, J., Baró, B., Bassat, Q., Pividori, M.I.“Traffic light-based Point-of-Care test for the rapid stratification of fever syndromes” (Poster), XXVIII Transfrontier Meeting on Sensors and Biosensors, La Ràpita (Spain), 26–27 September 2024.
Mussin, J., Giusiano, G., Porras, J., Corredor, L., Pividori, M.I. “Ensayo de flujo lateral basado en ADN para la detección de Paracoccidioides spp.” (Oral), XVI Congreso Argentino de Microbiología (CAM 2024), Palais Rouge, Ciudad Autónoma de Buenos Aires (Argentina), 21–23 August 2024.
Pividori, M.I. “Magnetic Separation of Exosomes with Tailored Magnetic Particles and Downstream Application” (Oral), 14th International Conference on the Scientific and Clinical Applications of Magnetic Carriers (MagMeet), Barcelona (Spain), 17–21 June 2024.
Rossi, R., Capdevila, M., Cano, A., Ruíz, A., Marti, M., Pividori, M.I. “Magnetic Particles Immunosensors for Early Diagnosis of Alzheimer’s Disease” (Poster), 14th International Conference on the Scientific and Clinical Applications of Magnetic Carriers (MagMeet), Barcelona (Spain), 17–21 June 2024.
Marfà, J., Pividori, M.I. “Magnetic molecularly imprinted polymers for the detection of pathogenic bacteria” (Poster), 14th International Conference on the Scientific and Clinical Applications of Magnetic Carriers (MagMeet), Barcelona (Spain), 17–21 June 2024.
Porras, J.C., Pallarès-Rusiñol, A., Alemany-López, K., Ferrer-Dalmau, J., Pividori, M.I. “Portable Medical Device Based on Magneto Immunosensor for the Diagnosis of Celiac Disorder” (Poster), 14th International Conference on the Scientific and Clinical Applications of Magnetic Carriers (MagMeet), Barcelona (Spain), 17–21 June 2024.
del Valle, A., Mesas, M., Fernández-Senac, C., Pallarès-Rusiñol, A., Martí, M., Baró, B., Ferrer-Dalmau, J., Bassat, Q., Pividori, M.I. “A magnetosensing-based Rapid Screening Test for Streptococcus agalactiae Infections: Expanding Global Efforts in Addressing Perinatal Sepsis” (Poster), 14th International Conference on the Scientific and Clinical Applications of Magnetic Carriers (MagMeet), Barcelona (Spain), 17–21 June 2024.
Mesas, M., del Valle, A., Martí, M., Pallarès-Rusiñol, A., Ferrer-Dalmau, J., Baró, B., Bassat, Q., Pividori, M.I.“Traffic light-based point-of-care test for the rapid stratification of fever syndromes” (Poster), 14th International Conference on the Scientific and Clinical Applications of Magnetic Carriers (MagMeet), Barcelona (Spain), 17–21 June 2024.
Bernuz, M., Porras, J.C., Egri, N., González-Navarro, E.A., Juan, M., Pividori, M.I., Martí, M. “Rapid Diagnostic Test for Assessment of Cellular Immune Response in a Viral Infection as a Model” (Poster), Federation of Clinical Immunology Societies (FOCIS) 2024, San Francisco (USA), 18–21 June 2024.
Bernuz, M., Porras, J.C., Egri, N., González-Navarro, E.A., Juan, M., Pividori, M.I., Martí, M. “Rapid Diagnostic Test for Assessment of Cellular Immune Response in a Viral Infection as a Model” (Poster), XV Jornada del Departament de Biologia Cel·lular, Fisiologia i Immunologia de la UAB, Universitat Autònoma de Barcelona (Spain), 13 June 2024. Best poster award
del Valle, A., Mesas, M., Pallarès-Rusiñol, A., Martí, M., Baró, B., Ferrer-Dalmau, J., Bassat, Q., Pividori, M.I.“Rapid screening test for Streptococcus agalactiae neonatal infections combining portable PCR and electrochemical genosensing” (Poster and oral), 13th Doctoral Workshop – PhD Programme in Chemistry, Sala d’Actes, Faculty of Sciences, Bellaterra (Spain), 23–24 May 2024.
Rossi, R., Capdevila, M., Cano, A., Ruíz, A., Marti, M., Pividori, M.I. “Exosome-Based Biosensing Platforms for Early Diagnosis of Alzheimer’s Disease” (Oral), 8th International Conference on Bio-Sensing Technology, Sevilla (Spain), 12–15 May 2024.
Marfà, J., Pividori, M.I. “Integration of molecularly imprinted polymers into paper-based nucleic acid lateral flow platforms for enhanced multiplexed point-of-need diagnostics” (Poster), 8th International Conference on Bio-Sensing Technology, Sevilla (Spain), 12–15 May 2024.
del Valle, A., Mesas, M., Fernández-Senac, C., Pallarès-Rusiñol, A., Martí, M., Baró, B., Ferrer-Dalmau, J., Bassat, Q., Pividori, M.I. “Rapid Screening Test for Streptococcus agalactiae Infections: A Step Towards Global Intervention in Perinatal Infections” (Poster), 8th International Conference on Bio-Sensing Technology, Sevilla (Spain), 12–15 May 2024.
Mesas, M., del Valle, A., Martí, M., Pallarès-Rusiñol, A., Ferrer-Dalmau, J., Baró, B., Bassat, Q., Pividori, M.I.“Traffic light-based point-of-care test for the rapid stratification of fever syndromes” (Poster), 8th International Conference on Bio-Sensing Technology, Sevilla (Spain), 12–15 May 2024.
Baró, B., Mesas, M., Pallarès, A., Balanza, N., Ajanovic, S., Millat-Martínez, P., Madrid, L., Varo, R., Sitoe, A., Mandomando, I., Kain, K., Ferrer-Dalmau, J., Bassat, Q., Pividori, M.I. “A quantitative point-of-care device based on measurement of sTREM-1 levels for risk-stratification of febrile patients” (Poster), 34th European Congress of Clinical Microbiology & Infectious Diseases (ECCMID), Barcelona (Spain), 27–30 April 2024.
Rossi, R., Capdevila, M., Cano, A., Ruíz, A., Marti, M., Pividori, M.I. “Exosome-Based Electrochemical Biosensing for Early Diagnosis of Alzheimer’s Disease” (Oral), AD/PD 2024 International Conference on Alzheimer’s and Parkinson’s Diseases and related neurological disorders, Lisbon (Portugal), 5–9 March 2024.
Rossi, R., Capdevila, M., Cano, A., Ruíz, A., Marti, M., Pividori, M.I. “Exosome-Based Electrochemical Biosensing for Early Diagnosis of Alzheimer’s Disease” (Oral), XXVII Transfrontier Meeting on Sensors and Biosensors, Banyuls-sur-Mer (France), 28–29 September 2023.
Bernuz, M., Porras, J.C., Juan, M., Pividori, M.I., Martí, M. “RDT for cellular immune response detection in viral infections in whole blood samples” (Oral), XXVII Transfrontier Meeting on Sensors and Biosensors, Banyuls-sur-Mer (France), 28–29 September 2023.
Marfà, J., Pividori, M.I. “Enhancing paper-based immunochromatography assays with molecularly imprinted polymers as testing zone” (Oral), XXVII Transfrontier Meeting on Sensors and Biosensors, Banyuls-sur-Mer (France), 28–29 September 2023.
del Valle, A., Mesas, M., Fernández-Senac, C., Pallarès-Rusiñol, A., Bernuz, M., Martí, M., Baró, B., Ferrer-Dalmau, J., Bassat, Q., Pividori, M.I. “Point-of-care rapid screening test for Streptococcus Agalactiae infections: a step towards global intervention in perinatal infections” (Poster), XXVII Transfrontier Meeting on Sensors and Biosensors, Banyuls-sur-Mer (France), 28–29 September 2023.
Mesas, M., del Valle, A., Martí, M., Pallarès-Rusiñol, A., Ferrer-Dalmau, J., Baró, B., Bassat, Q., Pividori, M.I.“Traffic light-based point-of-care test for the rapid stratification of fever syndromes” (Poster), XXVII Transfrontier Meeting on Sensors and Biosensors, Banyuls-sur-Mer (France), 28–29 September 2023.
Mesas, M.*, Romero, D., Armengou, L., Pividori, M.I. “Enhanced immunodetection of mare’s antibodies in colostrum samples for managing foal immunodeficiency: smartphone technology as a reading platform” (Poster), XXVII Transfrontier Meeting on Sensors and Biosensors, Banyuls-sur-Mer (France), 28–29 September 2023.
Mesas, M., Molina, B., Araújo, B., Boldrín Zanoni, M.V., Domínguez, J., Pividori, M.I. “The detection of Legionella pneumophila retained in filters is enhanced by immunomagnetic separation” (Poster), XXVII Transfrontier Meeting on Sensors and Biosensors, Banyuls-sur-Mer (France), 28–29 September 2023.
PUBLICATIONS
INDEXED
Rapid diagnostic test for assessment of cellular immune response in a viral infection as a model. Mireia Bernuz, Juan Carlos Porras, Natalia Egri, Europa Azucena González-Navarro, Manel Juan, María Isabel Pividori, Mercè Martí, Sensors & Actuators: B. Chemical, Volume 417, 15 October 2024, 136185, https://doi.org/10.1016/j.snb.2024.136185
Carbon nanoparticle-based lateral flow assay for the detection of specific double-tagged DNA amplicons of Paracoccidioides spp. Javier Mussin, Gustavo Giusiano, Juan Carlos Porras, Luis Hernando Corredor Sanguña, María Isabel Pividori, Microchimica Acta (2024) 191:287 https://doi.org/10.1007/s00604-024-06367-4
Evaluating smartphone-based optical readouts for immunoassays in human and veterinary healthcare: A comparative study. Melania Mesas Gómez, Esther Julián, Lara Armengou, Maria Isabel Pividori, 275, 2024, 126106, https://doi.org/10.1016/j.talanta.2024.126106
Peptide-based biosensing approaches for targeting breast cancer-derived exosomes. Rafael da Fonseca Alves, Arnau Pallarès-Rusiñol, Rosanna Rossi, Merce Martí , Emilia Rezende Vaz, Thaise Gonçalves de Araújo, Maria Del Pilar Taboada Sotomayor and Maria Isabel Pividori. Biosensors and Bioelectronics 255, 2024, 116211. https://doi.org/10.1016/j.bios.2024.116211
Replication data for: “Peptide-based biosensing approaches for targeting breast cancer-derived exosomes”. Rafael da Fonseca Alves, Arnau Pallarès-Rusiñol, Rosanna Rossi, Merce Martí , Emilia Rezende Vaz, Thaise Gonçalves de Araújo, Maria Del Pilar Taboada Sotomayor and Maria Isabel Pividori. 2024 | Data set. DOI: 10.34810/data1273
Mycobacterium detection method combining filtration, immunomagnetic separation, and electrochemical readout in a portable biosensing device. Melania Mesas Gómez, Bárbara Molina-Moya, Bárbara Camila de Araújo, Arnau Pallarès-Rusiñol, Jofre Ferrer-Dalmau, Maria Valnice Boldrín Zanoni, José Domínguez, Esther Julian, María Isabel Pividori Gurgo. Sensors & Actuators: B. Chemical 403 (2024) 135211 https://doi.org/10.1016/j.snb.2023.135211
Experimental data of the manuscript “Mycobacterium detection method combining filtration, immunomagnetic separation, and electrochemical readout in a portable biosensing device”. Melania Mesas Gómez, Bárbara Molina-Moya, Bárbara Camila de Araújo, Arnau Pallarès-Rusiñol, Jofre Ferrer-Dalmau, Maria Valnice Boldrín Zanoni, José Domínguez, Esther Julian, María Isabel Pividori Gurgo. 2024 | Data set. DOI: 10.34810/DATA1016
Improved biosensing of Legionella by integrating filtration and immunomagnetic separation of the bacteria retained in filters. Melania Mesas Gómez, Bárbara Molina‑Moya, Bárbara de Araujo Souza, Maria Valnice Boldrin Zanoni, Esther Julián, José Domínguez, Maria Isabel Pividori. (2024). Microchimica Acta (2024) 191:82 https://doi.org/10.1007/s00604-023-06122-1
Experimental data of the manuscript “Improved biosensing of Legionella by integrating filtration and immunomagnetic separation of the bacteria retained in filters”. Melania Mesas Gómez, Bárbara Molina‑Moya, Bárbara de Araujo Souza, Maria Valnice Boldrin Zanoni, Esther Julián, José Domínguez, Maria Isabel Pividori. 2024 | Data set. DOI: 10.34810/data1015
Plasma extracellular vesicles reveal early molecular differences in amyloid positive patients with early-onset mild cognitive impairment. Amanda Cano, Pablo García, Mireia Bernuz, Raquel Puerta, Itziar de Rojas, Ester Esteban-De Antonio, Alba Pérez-Cordón, Laura Montreal, Raúl Núñez, Óscar Sotolongo-Grau, Silvia Alonso-Lana, Emilio Alarcón-Martín, Sergi Valero, Montserrat Alegret, Joan Martínez, Elvira Martín, Miren Ettcheto, Assumpta Vivas, Marta Gomez-Chiari, Miguel Ángel Tejero, Adelina Orellana, Lluís Tárraga, Marta Marquié, Mercè Martí, María Isabel Pividori, Mercè Boada, Agustín Ruiz, Journal of Nanobiotechnology 2023, 21 (1), 1-19. https://doi.org/10.1186/s12951-023-01793-7
Extracellular vesicles, the emerging mirrors of brain physiopathology. Cano A, Ettcheto M, Bernuz M, Puerta R, Esteban de Antonio E, Sánchez-López E, Souto EB, Camins A, Martí M, Pividori MI, Boada M, Ruiz A. International Journal of Biological Sciences 2023 19(3):721-743. doi:10.7150/ijbs.79063
Electrochemical genosensing of overexpressed GAPDH transcripts in breast cancer exosomes. A Pallarès Rusiñol, Lima de Moura, M Martí, MI Pividori. Electrochemical genosensing of overexpressed GAPDH transcripts in breast cancer exosomes. Analytical chemistry, 2023, 95, 2487–2495 https://doi.org/10.1021/acs.analchem.2c04773.
Experimental data of the manuscript “Electrochemical Genosensing of Overexpressed GAPDH Transcripts in Breast Cancer Exosomes”. A Pallarès Rusiñol, Lima de Moura, M Martí, MI Pividori. Electrochemical genosensing of overexpressed GAPDH transcripts in breast cancer exosomes. 2023 | Data set. DOI: 10.34810/DATA681.
Advances in exosome analysis. A Pallares-Rusiñol, M Bernuz, S L Moura, C Fernández-Senac, R Rossi, M Martí and MI Pividori, in Advances in Clinical Chemistry 2023,112:69-117 https://doi.org/10.1016/bs.acc.2022.09.002 Extracellular vesicles, the emerging mirrors of brain physiopathology. Cano A, Ettcheto M, Bernuz M, Puerta R, Esteban de Antonio E, Sánchez-López E, Souto EB, Camins A, Martí M, Pividori MI, Boada M, Ruiz A. International Journal of Biological Sciences 19(3):721-743. doi:10.7150/ijbs.79063
OTHER PUBLICATIONS
Los exosomas. Nuevas herramientas para el diagnóstico de enfermedades no transmisibles en biopsias líquidas. Rosanna Rossi, Arnau Pallarès-Rusiñol, Mercé Martí, María Isabel Pividori. Actualidad Analítica 85, 2024, 15-20. ISSN 2444-8818. Sociedad española de química analítica.
Magnetic Separation of Cell-Secreted Vesicles with Tailored Magnetic Particles and Downstream Applications. Bernuz, M., Pallarès-Rusiñol, A., Rossi, R., Fernández-Senac, C., Martí, M., Pividori, M.I. (2023). In: Vainio, S. (eds) Cell-Secreted Vesicles. ‘Methods in Molecular Biology’, vol 2668. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-3203-1_18
Mesas, M., del Valle, A., Marfà, J., Porras, J.C., Pallarès-Rusiñol, A., Ferrer-Dalmau, J., Rossi, R., Martí, M., Pividori, M.I. (2024). Portable biosensing device for in vitro diagnostic. In Libro de resúmenes del 13º Congreso Iberoamericano de Sensores (IBERSENSOR 2024) (pp. 164). Buenos Aires, Argentina: Universidad Nacional de San Martín. ISBN: 978-987-8801-74-4.
Mesas, M., del Valle, A., Pallarès-Rusiñol, A., Ferrer-Dalmau, J., Martí, M., Baró, B., Bassat, Q., Pividori, M.I.(2024). Traffic light-based point-of-care test for the rapid stratification of fever syndromes. In Libro de resúmenes del 13º Congreso Iberoamericano de Sensores (IBERSENSOR 2024) (pp. 165). Buenos Aires, Argentina: Universidad Nacional de San Martín. ISBN: 978-987-8801-74-4
del Valle, A., Mesas, M., Pallarès-Rusiñol, A., Martí, M., Baró, B., Ferrer-Dalmau, J., Bassat, Q., Pividori, M.I. (2024). Rapid screening test for Streptococcus agalactiae neonatal infections combining portable PCR and electrochemical genosensing. In Libro de resúmenes del 13º Congreso Iberoamericano de Sensores (IBERSENSOR 2024) (pp. 226). Buenos Aires, Argentina: Universidad Nacional de San Martín. ISBN: 978-987-8801-74-4.
PATENTS
| Pividori, M. I. (2022). Device for Assay System, System and Method. PCT/EP2022/071078. Fecha de prioridad: 28/07/2021.2023 Publicación internacional: WO2023006817A1 2024 Extensiones nacionales en curso: Europa: EP4377009A1 Estados Unidos: US20240342702A1 Canadá: CA3225688A1Japón: JP2024527052A Estado de explotación: Actualmente licenciada a BioEclosion SL. Esta patente protege la arquitectura modular del lector electroquímico portátil, incluyendo su funcionamiento con batería o energía solar, la actuación magnética integrada y la compatibilidad con distintos biomarcadores sin necesidad de modificar el hardware. Pividori, M. I., Rossi, R., Martí, M. (2025). BACE-1 in brain-derived extracellular vesicles as a biomarker for Alzheimer’s disease. EP25382155.7. Fecha de prioridad: 20/02/2025.Estado de explotación: Patente en tramitación, actualmente no licenciada. Se encuentra en evaluación para su posible uso en plataformas de diagnóstico precoz de Alzheimer mediante detección de exosomas neuronales en plasma, dentro de la línea IVDimmunoSenS del proyecto. |
COMPLETED DOCTORAL THESES
• Jennifer Marfa Mora (Becaria FPI). Molecularly Imprinted Polymers targeting small labels for biomolecular design and their integration into paper-based diagnostic platforms. 19/12/2024. Director: MI Pividori. Universitat Autònoma de Barcelona. Excelente Cum Laude
• Mireia Bernuz Jimeno. (Becaria PIF). In vitro diagnostic designs for applications in health care. 22/04/2024. Director: MI Pividori/M. Martí. . Universitat Autònoma de Barcelona. Excelente Cum Laude
• Melania Mesas Gómez (Becaria FPI). In vitro diagnostic tests and biosensing devices for pathogenic bacteria in clinical and environmental settings. 1/03/2024. Director: MI Pividori. Universitat Autònoma de Barcelona. Excelente Cum Laude