ExoSenS. The exosomes as diagnostic biomarkers in biosensors

Exosomes are cell‐derived nanovesicles released into biological fluids, which are involved in physiological cell-to-cell communication, to maintain natural homeostasis and pathological responses. These vesicles are under intensive study as biomarkers for improving the clinical diagnosis and prognosis of different conditions. This proposal explores the use of the exosomes as a target in rapid test (RDTs) for the early diagnosis of communicable and non-communicable diseases and to meet the features for RDTs. All the developed strategies will assess a coherent business-focused analysis of research and innovation bottlenecks and opportunities to further societal challenges related with health and wellbeing.

This three year project is funded by Programa Estatal de Generación de Conocimiento y Fortalecimiento Científico y Tecnológico del Sistema de I+D+i y del Programa Estatal de I+D+i Orientada a los Retos de la Sociedad, en el marco del Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020.

Project Team

The project was led by Prof. Maria Isabel Pividori (UAB), who supervised the overall scientific and technological progress of the project and participated across all work packages (WP1–WP5). She was supported by Dr. Mercè Martí (UAB), co-IP of the project, who contributed to experimental design, biomarker selection, and validation strategies throughout WP1–WP4.  The working team brought together senior researchers, postdoctoral fellows, predoctoral researchers, and master students who collectively carried out the experimental activities within the different work packages. Among the senior researchers, Dr. María Pilar Taboada, Dr. Hideko Yamanaka, and Dr. Maria Valnice Boldrin Zanoni, all from UNESP (Brazil), contributed substantially to WP2 and WP4 through their recognized expertise in electrochemical biosensors, strengthening a long-standing UNESP–UAB collaboration established over more than a decade. Their involvement was complemented by several predoctoral researchers, including Silio Lima Moura, Melania Mesas, Arnau Pallarès, Jennifer Marfà, Mireia Bernuz, Andrea Aran, and Anaixis del Valle, who carried out extensive hands-on development in WP2–WP4, working on magnetic separation strategies, exosome and vesicle characterization, electrochemical measurements, and assay optimization. A second group of contributors consisted of master students who provided essential support to the laboratory work. Juan Carlos Porras, Marina Carrascal, Marta Gallardo, Marina Tuxans, Berta Solà, Zahra Gholami, Oriol Tomàs, and David Romero collaborated in sample processing, biosensor testing, and prototype-related tasks within WP2–WP4, completing their master’s theses in the framework of the project. The team also benefited from the participation of postdoctoral researchers who joined during the course of the project. Dr. Rosanna Rossi and Dr. Carolina Fernández-Senac, funded respectively through María Zambrano and Margarita Salas programs, contributed to WP2–WP4 through assay refinement and advanced biosensing strategies. Additionally, Dr. Javier Esteban Mussin, a RAÍCES postdoctoral fellow from Argentina, supported the experimental work in WP3 and WP4 with expertise in molecular diagnostics and analytical validation. International predoctoral researchers also played an important role. Rafael Fonseca Alves (FAPESP BEPE fellow, Brazil) and Camila Bulfoni (RAÍCES fellow, Argentina) contributed to WP2–WP4 through specialized work in exosome analysis, method optimization, and data acquisition, enriching the project with their global research experience. Together, this multidisciplinary and international team provided the scientific, technical, and clinical expertise necessary to advance the project and achieve its objectives within the established timeline.

Most important results

Publications

• Electrochemical Genosensing of Overexpressed GAPDH Transcripts in Breast Cancer Exosomes. A Pallares-Rusiñol, SL Moura, M Martí, MI Pividori. Analytical Chemistry 95 (4), 2487-2495 (2023) https://doi.org/10.1021/acs.analchem.2c04773 Categoría: CHEMISTRY, ANALYTICAL. Índice de impacto: 7,4. Q1. Citas: 1. OPEN ACCESS
• Plasma extracellular vesicles reveal early molecular differences in amyloid positive patients with early-onset mild cognitive impairment. Amanda Cano, Pablo García, Mireia Bernuz, Raquel Puerta, Itziar de Rojas, Ester Esteban-De Antonio, Alba Pérez-Cordón, Laura Montreal, Raúl Núñez, Óscar Sotolongo-Grau, Silvia Alonso-Lana, Emilio Alarcón-Martín, Sergi Valero, Montserrat Alegret, Joan Martínez, Elvira Martín, Miren Ettcheto, Assumpta Vivas, Marta Gomez-Chiari, Miguel Ángel Tejero, Adelina Orellana, Lluís Tárraga, Marta Marquié, Mercè Martí, María Isabel Pividori, Mercè Boada, Agustín Ruiz, Journal of Nanobiotechnology 2023, 21 (1), 1-19. https://doi.org/10.1186/s12951-023-01793-7 . Categoría: BIOTECHNOLOGY & APPLIED MICROBIOLOGY. Índice de impacto: 10.2. Q1. OPEN ACCESS
• Extracellular vesicles, the emerging mirrors of brain physiopathology. Cano A, Ettcheto M, Bernuz M, Puerta R, Esteban de Antonio E, Sánchez-López E, Souto EB, Camins A, Martí M, Pividori MI, Boada M, Ruiz A. International Journal of Biological Sciences 19(3):721-743. 2023. https://doi.org/10.7150/ijbs.79063. Categoría: BIOCHEMISTRY & MOLECULAR BIOLOGY. Índice de impacto: 9.2. Q1. Citas: 15 OPEN ACCESS
• Electrochemical Glyphosate Sensor Based on Hybrid Material SiO2/Sm2O3/Carbon Modified with Meldola Blue R Vieira Blasques, WS Fernandes‐Junior, AMR Vieira Mendes, …Maria Raimunda Chagas Silva, María Isabel Pividori, Paulo Cesar Mendes Villis.
  Electroanalysis 35 (5), e202200373 (2023). https://doi.org/10.1002/elan.202200373 Categoría: CHEMISTRY, ANALYTICAL . Índice de impacto: 3.0. Q2.
• The activity of alkaline phosphatase in breast cancer exosomes simplifies the biosensing design. Silio Lima de Moura, Arnau Pallarès Rusiñol, Luciano Sappia, Mercè Martí and MI Pividori. Biosensors and Bioelectronics 198, 113826. (2022) https://doi.org/10.1016/j.bios.2021.113826 Categoría: CHEMISTRY, ANALYTICAL. Índice de impacto: 12.6. Q1. Citas: 26. OPEN ACCESS
• A sensitive aptasensor using Biotin-Streptavidin system for patulin detection in apple juice. X Tang, Q Zhang, M Isabel Pividori, Z Zhang, JL Marty, G Catanante. Biosensors 12 (2), 59 (2022). https://doi.org/10.3390/bios12020059
  Categoría: CHEMISTRY, ANALYTICAL. Índice de impacto: 5,4. Q1. Citas: 2. OPEN ACCESS
• Immunomagnetic separation improves the detection of mycobacteria by paper-based lateral and vertical flow immunochromatographic assays. A Ben Aissa, B Araújo, E Julián, MV Boldrin Zanoni and MI Pividori. Sensors 2021, 21(18), 5992; (2021). https://doi.org/10.3390/s21185992. Selected for the cover. Categoría: INSTRUMENTS &
  INSTRUMENTATION. Índice de impacto: 3.847. Q1. Citas: 5. OPEN ACCESS
• Magnetic-molecularly imprinted polymers in electrochemical sensors and biosensors. J. Marfà, R.R. Pupin, MPT Sotomayor & M.I. Pividori. Analytical and Bioanalytical Chemistry 413, pp. 6141–6157 (2021). DOI: https://doi.org/10.1007/s00216-021-03461-x Categoría: CHEMISTRY, ANALYTICAL. Índice de impacto: 4.478. Q1 Citas: 15
• Development of magnetic nanoparticles modified with new molecularly imprinted polymer (MIPs) for selective analysis of glutathione. AC Ferreira Santos, ORP de Araújo, FA Moura, S Khan, AA Tanaka, AEG Santana, MI Pividori, MDPT Sotomayor, MOF Goulart. Sensors and Actuators B: Chemical, 2021, 344, 130171; (2021). https://doi.org/10.1016/j.snb.2021.130171. Categoría: CHEMISTRY, ANALYTICAL. Índice de impacto: 9,221. Q1. Citas: 13.
• Comparative Study of Gold and Carbon Nanoparticles in Nucleic Acid Lateral Flow Assay. Juan Carlos Porras, Mireia Bernuz, Jennifer Marfa, Arnau Pallares-Rusiñol, Mercè Martí and María Isabel Pividori, 2021, Nanomaterials 2021, 11(3), 741; https://doi.org/10.3390/nano11030741. Categoría: PHYSICS, APPLIED. Índice de impacto: 5,719. Q1. Citas: 11. OPEN ACCESS
• Assessment of the biological potential of diaryltriazene-derived triazene compounds. Patricia de Maria Silva Figueirêdo, …, María Isabel Pividori, Manfredo Hörner & Paulo Cesar Mendes Villis. Scientific Reports volume 11, Article number: 2541 (2021).
  https://doi.org/10.1038/s41598-021-81823-2
  Categoría: MULTIDISCIPLINARY SCIENCES. Índice de impacto: 4,997. Q1. Citas 4. OPEN ACCESS
• Electrochemical Genosensing of E. coli Based on Padlock Probes and Rolling Circle Amplification. Alejandra Ben Aissa, Narayanan Madaboosi, Mats Nilsson and Maria Isabel Pividori, 2021, Sensors 2021, 21(5), 1749; https://doi.org/10.3390/s21051749 Selected for the cover. Categoría: INSTRUMENTS &
  INSTRUMENTATION. Índice de impacto: 3.847. Q1. Citas: 5. OPEN ACCESS
• Immunomagnetic separation of Salmonella with tailored magnetic micro and nanocarriers. In Salmonella Methods and Protocols (third edition), ‘Methods in Molecular Biology’ by Humana Press, 2021, 2182:51-65. https://doi.org/10.1007/978-1-0716-0791-6_7
• Determination of Temporary Dye Basic Red 51 In Commercial Hair Dye, River Water And Wastewater From Hairdressing Salon Using Graphite-Epoxy Composite Electrode Modified With Magnetic Nanoparticles. GT Corrêa, JC de Souza, JP Silva, MI Pividori, MVB Zanoni. Microchemical Journal, 105485, 2020. https://doi.org/10.1016/j.microc.2020.105485 Categoría: CHEMISTRY, ANALYTICAL. Índice de impacto: 4,821. Q1. Citas; 6
• Osteoblastic exosomes. A non-destructive quantitative approach of alkaline phosphatase to assess osteoconductive nanomaterials. Maria Alejandra Sanchez, Betiana Felice, Luciano Sappia, Silio Lima-Moura, Mercè Martí, María Isabel Pividori. Materials Science & Engineering C, 115, 110931. (2020) https://doi.org/10.1016/j.msec.2020.110931 Categoría: MATERIALS SCIENCE,BIOMATERIALS. Índice de impacto: 7.328. Q1, Citas; 8
• Electrochemical immunosensing of nanovesicles as biomarkers for breast cancer. Silio Lima Moura, Carme García Martín, Mercè Martí, María Isabel Pividori. Biosensors and Bioelectronics 150, 111882. (2020) https://doi.org/10.1016/j.bios.2019.111882.
  Categoría: CHEMISTRY, ANALYTICAL. Índice de impacto: 10.618. Q1. Citas: 54.
• Biotinylated phosphorus dendrimers as control line in nucleic acid lateral flow tests. Laura Vidal, Alejandra Ben Aissa, Jordi Salabert, Jose Juan Jara, Adelina Vallribera, María Isabel Pividori, Rosa María Sebastián. Biomacromolecules, 2020, 21, 3, 1315-1323. https://doi.org/10.1021/acs.biomac.0c00161 . Categoría: CHEMISTRY, ORGANIC. Índice de impacto: 6,988. Q1. Citas: 6.
• Multiplex detection and characterization of breast cancer exosomes by magneto-actuated immunoassay. Silio Lima Moura, Carme García Martín, Mercè Martí, María Isabel Pividori. Talanta, 211, 120657 (2020). https://doi.org/10.1016/j.talanta.2019.120657
  Categoría: CHEMISTRY, ANALYTICAL. Índice de impacto: 6.057. Q1. Citas: 29.
• Synthesis and characterization of a new ceramic nanomaterial Sio2/Npssm2o3/C-graphite for the development of electrochemical sensors. Rodrigo Vieira Blasques, …, Jean-Louis Marty, María Isabel Pividori Gurgo, Gilvanda Silva Nunes, Paulo Cesar Mendes Villis. Materials Chemistry and Physics, 243, 122255. https://doi.org/10.1016/j.matchemphys.2019.122255k Categoría: MATERIALS SCIENCE, MULTIDISCIPLINARY. Índice de impacto: 4.094. Q1. Citas: 3
• Matrix Effect in the Isolation of Breast Cancer-Derived
  Nanovesicles by Immunomagnetic Separation and Electrochemical Immunosensing-A Comparative Study. Silio Lima Moura, Mercè Martí, María Isabel Pividori. Sensors, 20(4), 965 (2020). https://doi.org/10.3390/s20040965
  Categoría: INSTRUMENTS &
  INSTRUMENTATION. Índice de impacto: 3.576. Q1. Citas: 17 OPEN ACCESS

Other publications

• David Romero Sucarrat. Master en Experimentación en Química. “mHealth. Els dispositius com a eina en la salut I la seva aplicació en tècniques d’immunoassaig”. Universidad Autónoma de Barcelona, 2023.
• Marina Tuxans Serrano. Master en Immunologia. “Nano-flow cytometry methods for exosomas molecular characterization”. Universidad Autónoma de Barcelona, 2022
• Berta Solà Fustagueras. Master en Immunologia. Design and Optimization of a Magnetoassay for the Detection and Quantification of microRNAs. Universidad Autónoma de Barcelona, 2022.
• Zahra Gholami. Master in Advanced Nanoscience and Nanotechnology. “Vertical Flow Assay for the Rapid Detection of Exosomes by Enzyme Biomarkers in Clinical Diagnosis”. Universidad Autónoma de Barcelona, 2021.
• Marina Carrascal Lladós. Master en Experimentación en Química. “Pruebas de diagnóstico rápido para la detección de inmunodeficiencias en caballos”. Universidad Autónoma de Barcelona, 2021.
• Oriol Tomàs Badell. Vertical Flow Assay for the detection of exosomes based on enzymatic labelling. Master in industrial chemistry and introduction to chemical research, UAB. 2020.
• Marta Gallardo Caballero. Magneto actuated immunoassay for the specific capture and detection of neuron derived exosomes. Màster in Neurociències, UAB, 2020.
• uan Carlos Porras Marichal. Comparative study of gold and carbon nanoparticles in nucleic acid lateral flow assay. Master in industrial chemistry and introduction to chemical research, UAB. 2020.
• Resalte en negrita el personal del equipo de investigación Total publicaciones: 8
  

Chapter books

• Magnetic Separation of Cell-Secreted Vesicles with Tailored Magnetic Particles and Downstream Applications. Bernuz, M., Pallarès-Rusiñol, A., Rossi, R., Fernández-Senac, C., Martí, M., Pividori, M.I. (2023). In: Vainio, S. (eds) Cell-Secreted Vesicles. ‘Methods in Molecular Biology’, vol 2668. 2023. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-3203-1_1
• Advances in exosome analysis. A Pallares-Rusiñol, M Bernuz, S L Moura, C Fernández-Senac, R Rossi, M Martí and MI Pividori, in Advances in Clinical Chemistry 2023,112:69-117 https://doi.org/10.1016/bs.acc.2022.09.002 Categoría: MEDICAL LABORATORY TECHNOLOGY. Índice de impacto: 6.303. Q1.

Patent

• -2021. Device for assay system, system and method. Inventor: María Isabel Pividori. PCT/EP2022/071078 Date of priority: 28/07/2021, de la cual la IP es la inventora y la patente explotada por BioEclosion, SL.

Conference contributions

Keynote lecturer/ Invited

Awarded

• Authors: Mireia Bernuz, Juan Carlos Porras, Manel Juan, Maria Isabel Pividori, Mercè Martí Title: “Rapid test to detect cellular immune response against SARs-CoV-2”
  Type of participation: Oral communication Congress: TMSB 2022. XXVI Transfrontier Meeting on Sensors and Biosensors Date and place: 29-30/09/2022. Universitat de Barcelona Prize of the Jury to the Best Oral Communication.
• Authors: Juan Carlos Porras, Mireia Bernuz, Jennifer Marfà, Arnau Pallarès-Rusiñol, Mercè Martí, Maria Isabel Pividori Title: “Comparative study of gold and carbon nanoparticles in nucleic acid lateral flow assay” Type of participation: Oral communication Congress: TMSB 2022. XXVI Transfrontier Meeting on Sensors and Biosensors
  Date and place: 29-30/09/2022. Universitat de Barcelona Prize of the Audience to the Best Oral Communication.
• Authors: Rafael de Fonseca Alves, Arnau Pallarès-Rusiñol, Marina Tuxans-Serrano, Thaise Gonçalves de Araújo, Mercè Martí, Maria del Pilar T. Sotomayor, Maria Isabel Pividori Title: “Biosensing approaches based on recombinant peptide selected by phage display for breast cancer exosomes” Type of participation: Poster Congress: TMSB 2022. XXVI Transfrontier Meeting on Sensors and Biosensors Date and place: 29-30/09/2022. Universitat de Barcelona Prize of the Audience to the Best Poster Communication.
• Authors: M. Bernuz*, M. Gallardo, M. Martí. M.I. Pividori Title: “Magneto actuated immunoassay for the specific capture and detection of neuron derived exosomes for Alzheimer’s disease diagnostic” Type of participation: Poster Congress: New Horizons in Alzheimer’s Disease (Hybrid Edition) Date and place: 27-28 October 2021, Leuven, Belgium SAO Travel Grant
• Authors: A. Pallares-Rusiñol*, M. Martí, M.I. Pividori
  Title: “Novel methods for the detection of exosomes as biomarkers of non communicable diseases”
  Type of participation: Oral and Poster
  Congress: Xth Doctoral Workshop, Dept. of Chemistry. UAB
  Date and place: 26-28th May 2021. Universitat Autònoma de Barcelona
  Best Poster and Flash Presentation Award. 1st Prize
• Authors: M. Bernuz*, M. Martí, M.I. Pividori Title: “Novel strategies for rapid diagnosis tests with early diagnosis biomarkers” Type of participation: Oral and Poster Congress: Xth Doctoral Workshop, Dept. of Chemistry. UAB Date and place: 26-28th May 2021. Universitat Autònoma de Barcelona Best Poster and Flash Presentation Award. 2nd Prize

Other contributions

• Authors: M.I. Pividori
  Title: “Advances in biosensing devices for exosomes”
  Type of participation: Oral
  Congress: II IAdChem WORKSHOP. Materials for Biosensing and Bioimaging. Universidad Autónoma
  de Madrid.
  Date and place: 17/02/2023. Madrid, Spain
• Authors: M. Bernuz, A. Pallares-Rusiñol, R. Rossi, C. Fernández-Senac, M. Martí, M.I. Pividori
  Title: “Biosensing strategies for exosomes”
  Type of participation: Oral communication
  Congress: 12º Congresso Ibero-Americano de Sensores
  Date and place: 5-8/09/2022. Aveiro, Portugal
• Authors: Mireia Bernuz, Juan Carlos Porras, Manel Juan, Maria Isabel Pividori, Mercè Martí
  Title: “Rapid test to detect cellular immune response against SARs-CoV-2”
  Type of participation: Oral communication
  Congress: TMSB 2022. XXVI Transfrontier Meeting on Sensors and Biosensors
  Date and place: 29-30/09/2022. Universitat de Barcelona
  Prize of the Jury to the Best Oral Communication.
• Authors: Juan Carlos Porras, Mireia Bernuz, Jennifer Marfà, Arnau Pallarès-Rusiñol, Mercè Martí, Maria Isabel Pividori
  Title: “Comparative study of gold and carbon nanoparticles in nucleic acid lateral flow assay”
  Type of participation: Oral communication
  Congress: TMSB 2022. XXVI Transfrontier Meeting on Sensors and Biosensors
  Date and place: 29-30/09/2022. Universitat de Barcelona
  Prize of the Audience to the Best Oral Communication.
• Authors: Rafael de Fonseca Alves, Arnau Pallarès-Rusiñol, Marina Tuxans-Serrano, Thaise Gonçalves de Araújo, Mercè Martí, Maria del Pilar T. Sotomayor, Maria Isabel Pividori
  Title: “Biosensing approaches based on recombinant peptide selected by phage display for breast cancer exosomes”
  Type of participation: Poster
  Congress: TMSB 2022. XXVI Transfrontier Meeting on Sensors and Biosensors
  Date and place: 29-30/09/2022. Universitat de Barcelona
  Prize of the Audience to the Best Poster Communication.
• Authors: J. Marfà, M.I. Pividori
  Title: “Molecularly imprinted polymer as testing zone in paper-based vertical flow assay”
  Type of participation: Oral communication
  Congress: TMSB 2022. XXVI Transfrontier Meeting on Sensors and Biosensors
  Date and place: 29-30/09/2022. Universitat de Barcelona
• Authors: M. Mesas, B. Molina, J. Domínguez, M.I. Pividori
  Title: “Rapid test for the detection of mycobacterium tuberculosis”
  Type of participation: Oral communication
  Congress: TMSB 2022. XXVI Transfrontier Meeting on Sensors and Biosensors
  Date and place: 29-30/09/2022. Universitat de Barcelona
• Authors: C. Fernández-Senac, M Bernuz, M. Martí, B. Baró, J. Ferrer-Dalmau, Q. Bassat, M.I. Pividori
  Title: “Rapid test for group b streptococcus perinatal infections”
  Type of participation: Poster
  Congress: TMSB 2022. XXVI Transfrontier Meeting on Sensors and Biosensors
  Date and place: 29-30/09/2022. Universitat de Barcelona
• Authors: M. Tuxans Serrano, A. Pallarès Rusiñol, J. Farrés, M. Martí, M.I. Pividori
  Title: “Nano-flow cytometry method for the evaluation of aldehyde dehydrogenase activity in exosomes”
  Type of participation: Poster
  Congress: TMSB 2022. XXVI Transfrontier Meeting on Sensors and Biosensors
  Date and place: 29-30/09/2022. Universitat de Barcelona
• Authors: M. Bernuz, R. Rossi, A. Cano, M. Martí, M. I. Pividori
  Title: “Development of magneto actuated immunoassays for the specific capture and detection of neuron derived exosomes for early diagnosis of Alzheimer’s disease”
  Type of participation: Poster
  Congress: TMSB 2022. XXVI Transfrontier Meeting on Sensors and Biosensors
  Date and place: 29-30/09/2022. Universitat de Barcelona
• Authors: Juan Carlos Porras, Mireia Bernuz, Arnau Pallares Rusiñol, Merce Martí, Maria Isabel Pividori.
  Title: “Comparative study of gold and carbon nanoparticles in nucleic acid lateral flow assay”
  Type of participation: Poster
  Congress: 7th International Conference on Bio-Sensing Technology
  Date and place: 22-25/05/22, Sitges, Spain
• Authors: Jennifer Marfà, Maria Isabel Pividori
  Title: “Molecularly imprinted polymer as testing zone in paper-based vertical flow assay”
  Type of participation: Poster
  Congress: 7th International Conference on Bio-Sensing Technology
  Date and place: 22-25/05/22, Sitges, Spain
• Authors: Mireia Bernuz, Marta Gallardo, Amanda Cano, Mercè Boada, Mercè Martí, Maria Isabel Pividori
  Title: “Neuron derived exosomes as a biomarker for Alzheimer’s disease diagnosis”
  Type of participation: Poster
  Congress: 7th International Conference on Bio-Sensing Technology
  Date and place: 22-25/05/22, Sitges, Spain
• Authors: Melania Mesas, Bárbara Araujo, Maria Valnice Zanonni, Esther Julián, Maria Isabel Pividori
  Title: “Mycobacteria magneto-actuated immunoassay and smartphone readout”
  Type of participation: Poster
  Congress: 7th International Conference on Bio-Sensing Technology
  Date and place: 22-25/05/22, Sitges, Spain
• Authors: Melania Mesas, Bárbara Molina, Bárbara Araujo, Maria Valnice Zanonni, José Dominguez, Maria Isabel Pividori
  Title: “The detection of Legionella pneumophila retained in filters is enhanced by immunomagnetic separation”
  Type of participation: Poster
  Congress: 7th International Conference on Bio-Sensing Technology
  Date and place: 22-25/05/22, Sitges, Spain
• Authors: Arnau Pallarès-Rusiñol, Maria Isabel Pividori, Mercè Martí
  Title: “The alkaline phosphatase activity in exosomes can be visually detected in paper-based vertical flow assay”
  Type of participation: Oral communication
  Congress: 7th International Conference on Bio-Sensing Technology
  Date and place: 22-25/05/22, Sitges, Spain
• Authors: M. Bernuz*, M. Martí, M.I. Pividori
  Title: “Interferon gamma detection in nucleic acid lateral flow of activated lymphocytes”
  Type of participation: Oral
  Congress: XXV Transfrontier Meeting on Sensors and Biosensors. IRTA – Institut de Recerca en Tecnologies Alimentàries
  Date and place: 30th September 2021. Online
• Authors: A. Pallares-Rusiñol*, Z. Gholami, M. Martí, M.I. Pividori
  Title: “Vertical flow assay for exosomes characterization based on their intrinsic enzyme activity”
  Type of participation: Oral
  Congress: XXV Transfrontier Meeting on Sensors and Biosensors. IRTA – Institut de Recerca en Tecnologies Alimentàries
  Date and place: 30th September 2021. Online
• Authors: M. Mesas, J. Dominguez , M. Martí and M.I. Pividori
  Title: “Magneto-actuated immunoassay and magneto-actuated electrochemical immunosensor for enhancing the detection of Legionella pneumophila retained in filters”
  Type of participation: Oral
  Congress: XXV Transfrontier Meeting on Sensors and Biosensors. IRTA – Institut de Recerca en Tecnologies Alimentàries
  Date and place: 30th September 2021. Online
• Authors: J. Marfà (*), R.R. Pupin, A. Ben Aissa, M.D.P.T. Sotomayor, M.I. Pividori
  Title: “Biomimetic polymers as test line in nucleic acid lateral flow assays”
  Type of participation: Oral presentation
  Congress: XXV Transfrontier Meeting on Sensors and Biosensors. IRTA – Institut de Recerca en Tecnologies Alimentàries
  Date and place: 30th September 2021. Online
• Authors: Andrea Aran, Elisa Molina, Ferran Abancó, Vicente Marco Molina, José Pérez, Javier Cortés, Mercè Martí
  Title: “Comparative analysis and characterization of TCR repertoires in breast cancer TILs”.
  Type of participation: poster
  Congress: 6th European Congress of Immunology
  Place: online. Date: 1 to 4 September 2021
• Authors: Andrea Aran, Elisa Molina, Ferran Abancó, Vicente Marco Molina, José Pérez, Javier Cortés, Mercè Martí
  Title: “Comparative analysis and characterization of TCR repertoires in breast cancer TILs”.
  Type of participation: poster
  Congress: Virtual Keystone Symposia. Precision Oncology: Translating Discovery to the Clinic
  Place: online. Date: 21 to 24 June 2021
• Authors: M. Bernuz*, M. Martí, M.I. Pividori
  Title: “Rapid test for interferon gamma released from isolated lymphocytes in nucleic acid lateral flow”
  Type of participation: Oral
  Congress: 1a Jornada de Doctorands i Residents, Naïve Immunologists
  Date and place: 18th June 2021, UAB
• Authors: Andrea Aran, Elisa Molina, Ferran Abancó, Vicente Marco Molina, José Pérez, Javier Cortés, Mercè Martí
  Title: “Comparative analysis and characterization of TCR repertoires in breast cancer TILs”.
  Type of participation: oral communication
  Congress: XII Jornades Departament Biologia Cel·lular, Fisiologia i Immunologia
  Place: Bellaterra, Spain Date: 16 June 2021
• Authors: J. Marfà (*), R.R. Pupin, A. Ben Aissa, M.D.P.T. Sotomayor, M.I. Pividori
  Title: “Biomimetic polymers as test line in nucleic acid lateral flow assays”
  Type of participation: Oral presentation
  Congress: 1º Optobosens. Congreso virtual de la Red Nacional de Sensores y Biosensores Ópticos
  Date and place: 27-28th May 2021. Online
• Authors: M. Bernuz*, M. Martí, M.I. Pividori
  Title: “Interferon gamma detection in nucleic acid lateral flow of activated lymphocytes”
  Type of participation: Oral
  Congress: 1º Optobosens. Congreso virtual de la Red Nacional de Sensores y Biosensores Ópticos
  Date and place: 27-28th May 2021. Online
• Authors: J.C.Porras, M.Bernuz, J.Marfà, A.Pallares-Rusiñol, M.Martí, M.I.Pividori
  Title: “Comparative study of gold and carbon nanoparticles in nucleic acid lateral flow assay”
  Type of participation: Oral presentation
  Congress: 1º Optobosens. Congreso virtual de la Red Nacional de Sensores y Biosensores Ópticos
  Date and place: 27-28th May 2021. Online
• Authors: A. Pallares-Rusiñol*, Z. Gholami, M. Martí, M.I. Pividori
  Title: “Vertical flow assay for exosomes characterization based on their intrinsic enzyme activity”
  Type of participation: Oral
  Congress: 1º Optobosens. Congreso virtual de la Red Nacional de Sensores y Biosensores Ópticos
  Date and place: 27-28th May 2021. Online
• Authors: A M. Mesas, MI Pividori
  Title: “Preconcentration strategies based on solid phase and advanced materials for enhancing rapid tests”
  Type of participation: Oral and Poster
  Congress: Xth Doctoral Workshop, Dept. of Chemistry. UAB
  Date and place: 26-28th May 2021. Universitat Autònoma de Barcelona
• Authors: Andrea Aran, Elisa Molina, Ferran Abancó, Vicente Marco Molina, José Pérez, Javier Cortés, Mercè Martí
  Title: “Comparative analysis and characterization of TCR repertoires in breast cancer TILs”.
  Type of participation: poster
  Congress: 42 Congress of Spanish Society of Immunology (SEI)
  Place: online. Date: 24 to 26 March 2021
• Authors: Andrea Aran, Elisa Molina, Ferran Abancó, Vicente Marco Molina, José Pérez, Javier Cortés, Mercè Martí
  Title: “Comparative analysis and characterization of TCR repertoires in breast cancer TILs”.
  Type of participation: oral communication
  Congress: 42 Congress of Spanish Society of Immunology (SEI)
  Place: online. Date: 19 to 20 November 2020

Doctoral Thesis

• Nombre: Alejandra Ben Aissa (Becaria Personal de Investigació en Formació, PIF).
  Director/a: MI Pividori
  Título: “Rapid diagnostic test for the detection of communicable diseases”
  Organismo: Universitat Autònoma de Barcelona. 03/09/2020 FINALIZADA
  
• Nombre: Silio Lima Moura (Becario Ciencias sin Fronteras, Brasil)
  Director/a: Pividori, María Isabel / Martí Ripoll, Mercè
  Título: From preconcentration to rapid detection of exosomes as biomarkers in clinical diagnosis. Premio extraordinario/Outstanding thesis award.
  Organismo: Universitat Autònoma de Barcelona. 27/07/2020 FINALIZADA
  
• Nombre: Pallarès Rusiñol, Arnau (Becario FPU)
  Director/a: Pividori, María Isabel / Martí Ripoll, Mercè
  Título: Novel methods for the detection of exosomes as biomarkers for non-communicable diseases
  Organismo: Universitat Autònoma de Barcelona. 04/11/2022 FINALIZADA
  Nombre: Melania Mesas Gómez (Becaria FPI)
  Director/a: Pividori, María Isabel